Engineered E. coli delivers therapeutic nanobodies to the gut
Humans are colonized with thousands of bacterial strains. Researchers are now focused on genetically modifying such bacteria to enhance their intrinsic therapeutic properties.
Humans are colonized with thousands of bacterial strains. Researchers are now focused on genetically modifying such bacteria to enhance their intrinsic therapeutic properties.
Cell & Microbiology
Mar 31, 2023
0
74
Antibiotic resistance (ARE) is a threat to human health worldwide, as diverse proteins allow pathogenic bacteria to develop increasing levels of resistance to antibiotic medicines. Now, a team from the University of Tsukuba ...
Cell & Microbiology
Mar 30, 2023
0
4
Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have harnessed a natural bacterial system to develop a new protein delivery approach that works in human cells and ...
Cell & Microbiology
Mar 29, 2023
0
51
The rapid spread of COVID-19 may have been partly due to changes in the structure of the SARS-CoV-2 virus wrought by an early mutation in its genome, a detailed analysis by RIKEN researchers suggests. The finding, published ...
Molecular & Computational biology
Mar 27, 2023
0
55
A parasite which has devastating impacts on agriculture and human health is the first pathogen to have its proteins located and mapped within its cells—providing clues to their function and helping to identify potential ...
Cell & Microbiology
Mar 24, 2023
0
68
A protein complex prevents the repair of genome damage in human cells, in mice and in the nematode Caenorhabditis elegans, a team of researchers at the University of Cologne has discovered. They also successfully inhibited ...
Cell & Microbiology
Mar 23, 2023
0
196
A major puzzle of biology is that while the human genome contains roughly 20,000 genes, many comparatively primitive organisms—including the universally-studied worm C. elegans—have almost the same number of genes.
Biotechnology
Mar 23, 2023
1
133
Researchers at Karolinska Institutet, Department of Medicine, Solna, have identified HOXC13-AS, a human skin-specific long noncoding RNA (lncRNA), that plays a crucial role in epidermal differentiation. Their study highlighting ...
Cell & Microbiology
Mar 22, 2023
0
59
Using an RNA sensor, MIT engineers have designed a new way to trigger cells to turn on a synthetic gene. Their approach could make it possible to create targeted therapies for cancer and other diseases, by ensuring that synthetic ...
Biotechnology
Mar 16, 2023
0
14
Scientists at the Department of Energy's Oak Ridge National Laboratory have confirmed that bacteria-killing viruses called bacteriophages deploy a sneaky tactic when targeting their hosts: They use a standard genetic code ...
Cell & Microbiology
Mar 16, 2023
0
46