Related topics: pluripotent stem cells

Turning off 'junk DNA' may free stem cells to become neurons

For every cell in the body there comes a time when it must decide what it wants to do for the rest of its life. In an article published in the journal PNAS, NIH researchers report for the first time that ancient viral genes ...

Scientists find optimal age of stem cells

Biophysicists from the Moscow Institute of Physics and Technology and Vladimirsky Moscow Regional Clinical Research Institute have determined the optimal age of reprogrammed stem cells suitable for restoring heart tissue. ...

Taming CRISPR's collateral damage

CRISPR-Cas9 can alter genes at pre-defined sites in specific ways, but it does not always act as planned. An LMU team has now developed a simple method to detect unintended "on-target" events, and shown that they often occur ...

Pros and cons of genetic scissors

Crispr technology has greatly facilitated gene editing. Associate Professor Thorsten Müller from Ruhr-Universität Bochum and Dr. Hassan Bukhari from Harvard Medical School discuss its pros and cons in a review article in ...

Brain waves detected in mini-brains grown in a dish

Scientists have created miniature brains from stem cells that developed functional neural networks. Despite being a million times smaller than human brains, these lab-grown brains are the first observed to produce brain waves ...

Chimpanzee 'mini-brains' hint at secrets of human evolution

At some point during human evolution, a handful of genetic changes triggered a dramatic threefold expansion of the brain's neocortex, the wrinkly outermost layer of brain tissue responsible for everything from language to ...

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