Decoding the cell signals between young proteins and their 'chaperones'
Of the 25,000 different proteins in the human body, insulin, antibodies, and collagen are among the few that perform their biological jobs by literally folding into 3D shapes.
Of the 25,000 different proteins in the human body, insulin, antibodies, and collagen are among the few that perform their biological jobs by literally folding into 3D shapes.
Cell & Microbiology
Dec 5, 2022
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It is widely understood that antibodies neutralize viruses by latching onto their surfaces and blocking them from infecting host cells. But new research reveals that this barrier method isn't the only way that antibodies ...
Cell & Microbiology
Nov 30, 2021
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606
A multi-institutional team led by researchers at Vanderbilt University Medical Center has isolated monoclonal antibodies that in laboratory and animal studies prevented infection by alphaviruses, including the often-lethal ...
Cell & Microbiology
Aug 20, 2021
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260
In the course of a new and groundbreaking study, led by Dr. Natalia Freund and the doctoral candidate Avia Watson at the Sackler Medical Faculty, the research group succeeded in isolating monoclonal antibodies, which hindered ...
Cell & Microbiology
Feb 22, 2021
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43
An antibody that can stop the new coronavirus infecting cells in laboratory tests has been identified by researchers in the Netherlands, in what scientists say could help the development of therapies for COVID-19.
Cell & Microbiology
May 5, 2020
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17
Despite efforts to contain it, bird flu remains a serious menace to public health.
Cell & Microbiology
Dec 16, 2019
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35
According to the World Health Organization, about 100,000 people die from venomous snakebites every year. Many of these fatalities occur in rural areas of developing countries that lack access to antivenoms. That's why researchers ...
Other
Jan 30, 2019
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4
Researchers at Vanderbilt University Medical Center and colleagues have isolated a human monoclonal antibody that can "neutralize" the West Nile virus and potentially prevent a leading cause of viral encephalitis (brain inflammation) ...
Cell & Microbiology
Nov 20, 2018
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200
Why some biopharmaceuticals have a longer shelf life than others is a problem that has baffled scientists and manufacturers alike. Even the same medication, produced by different manufacturers, can vary in its storage life.
Biochemistry
Sep 28, 2018
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10
Clostridium difficile (C. difficile) infection is the leading cause of hospital-acquired diarrhea, causing nearly a half million infections in the United States each year. Recurrence after treatment with antibiotics is common ...
Biochemistry
Jan 26, 2018
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10