Transcription factors could be the Swiss Army knives of gene regulation; they are versatile proteins containing multiple specialized regions. On one end they have a region that can bind to DNA. On the other end they have ...
Cell & Microbiology
Jul 5, 2023
0
17
Gene expression within the apicoplast, an organelle in the malaria parasite Plasmodium falciparum, is regulated by melatonin (the circadian signaling hormone) in host blood and intrinsic parasite cues, via a factor called ...
Cell & Microbiology
Jul 3, 2023
0
24
Artificial intelligence can predict on- and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology.
Biotechnology
Jul 3, 2023
0
4643
The tumor suppressor protein p53 has been dubbed the "guardian of the genome" because it protects the DNA from stress or long-term damage by regulating the expression of numerous genes involved DNA repair, cell division and ...
Molecular & Computational biology
Jun 30, 2023
0
50
CRISPR gene editing is a breakthrough that has been used to treat diseases such as sickle cell anemia, leukemia and genetic disorders, but it has challenges that limit its broad utility.
Biotechnology
Jun 29, 2023
0
15
A team of researchers led by Feng Zhang at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT has uncovered the first programmable RNA-guided system in eukaryotes—organisms that ...
Biotechnology
Jun 28, 2023
0
1696
The human gut hosts a complex ecosystem comprising an intricate plasmidome with abundant undiscovered plasmids, driving horizontal gene transfer events.
Cell & Microbiology
Jun 28, 2023
0
27
Cells in the human body, the building blocks of life, are arranged in a precise way. That's necessary because pathways and spaces provide a means for cells to communicate, collaborate and function within the specific tissue ...
Cell & Microbiology
Jun 26, 2023
0
6
A study led by Duke University has looked into the operating mechanisms of Akkermansia muciniphila, a gut microbe associated with lower rates of metabolic disorders.
Scientists studying gene activity data of the early human embryo have discovered an overlooked type of cell that self-destructs within days of forming, as part of a quality control process to protect the developing fetus. ...
Cell & Microbiology
Jun 20, 2023
0
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