Related topics: genes

Flaws emerge in modeling human genetic diseases in animals

My lab, based at the University of Southern California Keck School of Medicine, uses zebrafish to model human birth defects affecting the face. When I tell people this, they are often skeptical that fish biology has any relevance ...

'Monster tumors' could offer new glimpse at human development

Finding just the right model to study human development—from the early embryonic stage onward—has been a challenge for scientists over the last decade. Now, bioengineers at the University of California San Diego have ...

A groundbreaking genetic screening tool for human organoids

Many of the fundamental principles in biology and essentially all pathways regulating development were identified in so-called genetics screens. Originally pioneered in the fruit fly Drosophila and the nematode C. elegans, ...

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