Virulence factor of the influenza A virus mapped in real-time

The influenza A viruses, which are responsible for deadly pandemics in the past, still remain a major global public health problem today. Molecules known as virulence factors are produced by bacteria, viruses, and fungi to ...

Restricting HIV-1 infection

The HIV-1 capsid protein (CA) interacts with viral factors that support infection and host factors that restrict it. The host protein cyclophilin A (CypA) binds to CA and enhances the action of host restriction factors that ...

Disease burden links ecology to economic growth

A new study, published December 27 in the open access journal PLOS Biology, finds that vector-borne and parasitic diseases have substantial effects on economic development across the globe, and are major drivers of differences ...

Virus exploitscellular waste disposal system

ETH Zurich researchers demonstrate how vaccinia virus manipulates the cellular waste-disposal system and thereby cleverly tricks the cell into assisting the intruders replication. Now, the virologists have turned the tables, ...

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