E3 ubiquitin ligase plays essential role during rice meiosis

Synaptonemal complex (SC) assembly between paired homologous chromosomes plays a vital role in ensuring correct homologous recombination during meiosis. However, the mechanisms underlying the genetic regulation of SC assembly ...

Cellular aging: A basic paradox elucidated

In a study published in Nucleic Acids Research, the team of cancer researcher Francis Rodier, an Université de Montréal professor, shows for the first time that cellular senescence, which occurs when aging cells stop dividing, ...

The path(way) less traveled in DNA double-strand break repair

BRCA1, a protein that is well-known for its role in hereditary breast cancer, is an important part of the cellular system that repairs double-strand DNA breaks. Now, researchers from Japan have discovered a new way in which ...

Meiosis: Mind the gap

Scientists from the lab of Franz Klein from the Department of Chromosome Biology at the Max Perutz Labs, a joint venture of the University of Vienna and the Medical University of Vienna, have now discovered that cells sometimes ...

Study shows how some bacteria withstand antibiotic onslaught

In a study with implications for chronic infections, Princeton researchers have described multiple pathways that some bacteria use to tolerate normally lethal antibiotic treatments. The findings overturn common assumptions ...

Histone degradation after DNA damage enhances repair

DNA damage can occur anywhere in the genome, but most DNA is wrapped around nucleosomes making it inaccessible to the repair machinery. Researchers from the Gasser group now show that DNA damage induces histone depletion, ...

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