The year ahead in science
Some serious groundwork has been laid. Some amazing instruments are turning on. Some incredible destinations are in sight. If you ask us, 2015 is going to be an awesome year in science.
Some serious groundwork has been laid. Some amazing instruments are turning on. Some incredible destinations are in sight. If you ask us, 2015 is going to be an awesome year in science.
Other
Jan 5, 2015
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Limited success in modelling the behaviour of the complex, unusual and unpredictable HIV virus has slowed efforts to develop an effective vaccine to prevent AIDS.
General Physics
Apr 29, 2010
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(PhysOrg.com) -- Oxford research suggests the chains of sugar molecules, or carbohydrates, that cover the outside of the highly variable HIV virus remain constant, are different from those found on human cells, and could ...
Biochemistry
Jul 20, 2010
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(PhysOrg.com) -- There is now a promising vaccine candidate for combating the pathogen which causes one of the most common and dangerous hospital infections. An international team of scientists from the Max Planck Institute ...
Biochemistry
May 31, 2011
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By folding DNA into a virus-like structure, MIT researchers have designed HIV-like particles that provoke a strong immune response from human immune cells grown in a lab dish. Such particles might eventually be used as an ...
Bio & Medicine
Jun 29, 2020
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To many, EV stands for "electric vehicle." To researchers at Harvard University and the University of Nebraska–Lincoln, it's shorthand for another vehicle—this one nanoscopic—that might help streamline the development ...
Bio & Medicine
Jan 30, 2023
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A former Iowa State University scientist who altered blood samples to make it appear he had achieved a breakthrough toward a potential vaccine against HIV was sentenced Wednesday to more than 4 ½ years in prison for making ...
Other
Jul 1, 2015
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An HIV vaccine is a hypothetical vaccine against HIV, the etiological agent of AIDS. As there is no known cure for AIDS, the search for a vaccine has become part of the struggle against the disease.
The urgency of the search for a vaccine against HIV stems from the AIDS-related death toll of over 25 million people since 1981. Indeed, in 2002, AIDS became the primary cause of mortality due to an infectious agent in Africa.
Alternative medical treatments to a vaccine do exist. Highly active antiretroviral therapy (HAART) has been highly beneficial to many HIV-infected individuals since its introduction in 1996 when the protease inhibitor-based HAART initially became available. HAART allows the stabilization of the patient’s symptoms and viremia, but they do not cure the patient of HIV, nor of the symptoms of AIDS. And, importantly, HAART does nothing to prevent the spread of HIV through people with undiagnosed HIV infections. Safer sex measures have also proven insufficient to halt the spread of AIDS in the worst affected countries, despite some success in reducing infection rates.
Therefore, an HIV vaccine is generally considered as the most likely, and perhaps the only way by which the AIDS pandemic can be halted. However, after over 20 years of research, HIV-1 remains a difficult target for a vaccine.
The human body can defend itself against HIV, as work with monoclonal antibodies (MAb) has proven. That certain individuals can be asymptomatic for decades after infection is encouraging.
This text uses material from Wikipedia, licensed under CC BY-SA