Research by Kai Jiao, M.D., Ph.D., and colleagues at the University of Alabama at Birmingham and in Germany has yielded fundamental insights into the causes of severe birth defects known as CHARGE syndrome cases. These congenital ...
Molecular & Computational biology
Dec 3, 2020
0
17
Researchers at the University of Warwick have uncovered the mechanism that allows plants to pass on their 'memories' to offspring, which results in growth and developmental defects.
Plants & Animals
Dec 1, 2020
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35
A study lead by SciLifeLab Fellow Simon Elsässer elucidates the mechanism of a peculiar type of heterochromatin, used by embryonic stem cells to silence 'parasitic' DNA-elements within the context of their highly dynamic ...
Cell & Microbiology
Oct 9, 2020
0
8
Results of recent studies involving valproic acid, used for decades as an anti-convulsant drug, show that it can interact with the conformation of DNA and regulate gene expression.
Cell & Microbiology
Sep 28, 2020
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6
DNA damage can occur anywhere in the genome, but most DNA is wrapped around nucleosomes making it inaccessible to the repair machinery. Researchers from the Gasser group now show that DNA damage induces histone depletion, ...
Molecular & Computational biology
Sep 24, 2020
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31
A team of researchers at the University of California has found that the histone H3-H4 tetramer is a copper reductase enzyme. In their paper published in the journal Science, the group describes two experiments they carried ...
Inside our cells, DNA is tightly packed and spooled around proteins called histones. Packaging DNA in this way allows large amounts of genetic material to exist inside the cell in a final form called chromatin. Tiny enzymes ...
Cell & Microbiology
Jun 9, 2020
0
25
Parents pass genes along to their offspring traits that equip them for life. In recent years, research has shown that the reality is much more complex and that parents endow much more than just genes. A new study in Cell ...
Evolution
Jun 4, 2020
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1055
A group of scientists from CECAD has found a mechanism by which neurodevelopmental diseases concerning neurons can be explained. The loss of a certain enzyme, UBE2K, impedes the differentiation of stem cells by silencing ...
Cell & Microbiology
Jun 4, 2020
0
2
Although they do it differently than humans, plants also have memories. For example, many plants can sense and remember prolonged cold in the Winter to ensure they flower at the right time during the Spring. This so-called ...
Plants & Animals
May 14, 2020
0
80
