Mapping how cell types and tissues develop

Researchers have developed a technique that allows them to look simultaneously at a spatial level and at a genome-wide level at epigenetic mechanisms underlying tissue development, a breakthrough with multiple scientific ...

A histone modification essential for tissue integrity

Chemical modifications of histones, the small proteins around which DNA is wrapped, are known to affect gene expression. In a study conducted in C. elegans, researchers from the Gasser group show that the defining modification ...

Computer simulations animate in atomic detail how DNA opens

Researchers from the Hubrecht Institute in Utrecht (The Netherlands) and the Max Planck Institute for Molecular Biomedicine in M√ľnster (Germany) used computer simulations to reveal in atomic detail how a short piece of DNA ...

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