"Metabolism" describes the body's chemical changes that create the necessary materials for growth and overall health. Metabolites are the substances made and used during these metabolic processes—or, as a new discovery ...
Biochemistry
Oct 13, 2022
0
172
Scientists at EPFL have found a way to synthesize large numbers of macrocyclic compounds, which are needed for developing drugs against difficult disease targets.
Biochemistry
Jul 12, 2022
0
28
The chemical industry has only scratched the surface of possible molecules that could be used as drugs, which is unimaginably greater than the number of stars in the universe. To make navigating this vast chemical space more ...
Other
Jun 30, 2022
0
12
Proteins are the molecular machines of all living cells and have been exploited for use in many applications, including therapeutics and industrial catalysts. To overcome the limitations of naturally occurring proteins, protein ...
Biotechnology
Oct 8, 2021
0
176
A research team of pharmacists at the University of Bonn has discovered two families of active substances that can block the replication of the SARS-CoV-2 coronavirus. The drug candidates are able to switch off the the key ...
Biochemistry
Mar 3, 2021
1
66
Macrocyclic peptides are promising candidates for pharmaceuticals, but their screening is difficult. Scientists have now developed an easy-to-use, high-throughput screening assay for cyclic peptides with affinity to ubiquitin, ...
Biochemistry
Feb 22, 2021
0
13
Researchers have developed a human cell 'membrane on a chip' that allows continuous monitoring of how drugs and infectious agents interact with our cells, and may soon be used to test potential drug candidates for COVID-19.
Bio & Medicine
Jul 6, 2020
0
357
Researchers have engineered bacteria to produce new versions of a potential antibiotic molecule, some with potent antimalarial properties.
Biochemistry
May 7, 2020
0
50
A research team at the VIB-KU Leuven Center for Microbiology and the KU Leuven Department of Biology showed that, contrary to generally held belief, most components of essential oils could meet the criteria set for drug candidates. ...
Analytical Chemistry
Feb 21, 2020
3
3
RUDN University chemist Erik Van der Eycken has come up with a new method for the synthesis of a large group of complex poly-heterocyclic organic compounds, which may have applications for new pharmaceuticals. The researcher ...
Materials Science
Oct 29, 2019
0
23
