Photoluminescent probes with high biocompatibility, quantum yield and multiphoton absorption performance are of significant interest in biomedical imaging, expected to achieve improved penetration depth and spatial resolution. ...
A particularly aggressive, metastasizing form of cancer, HER2-positive breast cancer, may be treated with nanoscopic particles "imprinted" with specific binding sites for the receptor molecule HER2. As reported by Chinese ...
Bio & Medicine
Jul 3, 2019
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According to the Mayo Clinic, about 20% of breast cancers make abnormally high levels of a protein called human epidermal growth factor receptor 2 (HER2). When displayed on the surface of cancer cells, this signaling protein ...
Bio & Medicine
Jun 5, 2019
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Antibody-based imaging of a particularly aggressive form of breast cancer is undergoing clinical trials worldwide, but the path from trial to application is being hampered by a major obstacle: safety.
Bio & Medicine
Oct 11, 2018
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85
Researchers at the University of Cincinnati (UC) College of Medicine have been able to generate multifunctional RNA nanoparticles that could overcome treatment resistance in breast cancer, potentially making existing treatments ...
Bio & Medicine
Dec 14, 2016
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(Phys.org) —Herceptin and camptothecin are both powerful anticancer agents with key characteristics that limit their effectiveness in treating cancer. Patients treated with Herceptin, a monoclonal antibody that targets ...
Bio & Medicine
Jul 15, 2013
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(Phys.org) —Identify the type of cancer for patients with breast cancer in a few minutes. This is the challenge that EPFL researchers successfully met by presenting their new "microfluidic chip." Their research is written ...
Engineering
Apr 2, 2013
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Many cancer therapies target specific proteins that proliferate on the outside of some cancer cells, but the therapies are imperfect and the cancer does not always respond. Since it is beneficial for doctors to know as soon ...
Optics & Photonics
Dec 20, 2011
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One hallmark of cancer cells is uncontrollable growth, provoked by inappropriate signals that instruct the cells to keep dividing. Researchers at MIT and Brigham and Women’s Hospital have now identified a new way to ...
Biochemistry
Jun 13, 2011
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Researchers at Rice University, collaborating with investigators at the Baylor College of Medicine, have used two different types of imaging technologies to track the delivery of a therapeutic nanoparticle to breast tumors. ...
Bio & Medicine
Dec 17, 2010
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HER2/neu (also known as ErbB-2) stands for "Human Epidermal growth factor Receptor 2" and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2/neu has also been designated as CD340 (cluster of differentiation 340) and p185. It is encoded by the ERBB2 gene.
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