Endothelial cells (ECs) line blood vessels and can serve as specialized vascular niches for hematopoietic stem and progenitor cells (HSPCs), a special environment where HSPCs reside and self-renew. A team of researchers found ...
Cell & Microbiology
Jan 24, 2023
0
70
A new statistical method provides a more efficient way to uncover biologically meaningful changes in genomic data that span multiple conditions—such as cell types or tissues.
Molecular & Computational biology
Nov 14, 2022
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56
Mitochondria may seem like small cogs in the complex machinery of the cell, but even little gears can drive big changes. Now, researchers from Japan have found that impairing mitochondria in two different ways can have a ...
Cell & Microbiology
Oct 13, 2022
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6
A well-functioning immune system is essential for protection against infections. However, with increasing age, the functioning of the immune system diminishes, which is also due to age-related damage in hematopoietic (blood) ...
Cell & Microbiology
Oct 10, 2022
0
116
The fetal liver is the major hematopoietic organ during the embryonic stage. It is generally believed that hematopoietic hierarchy in the fetal liver is established through the differentiation of fetal hematopoietic stem ...
Cell & Microbiology
Sep 21, 2022
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58
Astronauts are at higher risk for developing mutations—possibly linked to spaceflight—that can increase the risk of developing cancer and heart disease during their lifetimes, according to a first-of-its kind study from ...
Space Exploration
Aug 31, 2022
0
371
Enhancement of adhesion molecules improves the ability of blood-forming stem cells to take root in transplant recipients.
Cell & Microbiology
Aug 25, 2022
0
13
The molecular tool CRISPR-Cas9 can be used to treat inherited blood disorders, but this may cause unintended genetic alterations. A team led by MDC researchers Klaus Rajewsky and Van Trung Chu has now presented an approach ...
Biotechnology
Jun 23, 2022
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37
Throughout one's life, the blood is constantly being replenished from blood stem cells. However, these cells lose their functionality in old age. Researchers at the Leibniz Institute on Aging—Fritz Lipmann Institute (FLI) ...
Cell & Microbiology
Jun 17, 2022
0
31
The origins of our blood may not be quite what we thought. Using cellular "barcoding" in mice, a groundbreaking study finds that blood cells originate not from one type of mother cell, but two, with potential implications ...
Cell & Microbiology
Jun 15, 2022
0
136
