A protein safeguards against cataracts

The refractive power of the human eye lens relies on a densely packed mixture of proteins. Special protective proteins ensure that these proteins do not clump together as time passes. When this protective mechanism fails, ...

Study uncovers secrets of a clump-dissolving protein

Workhorse molecules called heat-shock proteins contribute to refolding proteins that were once misfolded and clumped, causing such disorders as Parkinson's disease, amyotrophic lateral sclerosis, and Alzheimer's disease. ...

Researchers discover new pathway for handling stress

Balance is key to many physiological functions and it is especially true in the production and regulation of proteins. A balance of proteins in cells helps maintain health, but an unhealthy clumping can lead to a variety ...

A chaperone for the 'guardian of the genome'

The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, ...

Scientists sleuth out proteins involved in Crohn's disease

(Phys.org) —University of Delaware researchers have identified a protein, hiding in plain sight, that acts like a bodyguard to help protect and stabilize another key protein, that when unstable, is involved in Crohn's disease. ...

Scientists discover new function of heat-shock protein

An international research team has identified a new function of Hsp90, one of the most common and studied proteins in the human body. The study has implications for the development of new drugs.

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