Study demonstrates 'tunability' of a molecular chaperone

For decades, molecular biologists studying a class of molecular chaperones known as heat shock proteins (Hsp70s) have relied on the Hsp70s found in bacteria as the model system. Now one of the world's experts on the molecule ...

Cellular stress defense

Small heat-shock proteins (sHSPs) are molecular chaperones that bind to unfolded proteins to prevent protein aggregation and defend against cellular stress. Mutations in human sHSPs are associated with inherited diseases ...

Scientists discover new function of heat-shock protein

An international research team has identified a new function of Hsp90, one of the most common and studied proteins in the human body. The study has implications for the development of new drugs.

Hsp90—more than just a chaperone

Researchers from the Verstreken lab (VIB-KU Leuven) have identified a completely novel function for Hsp90, one of the most common and most studied proteins in our body. In addition to its well-known role as a protein chaperone, ...

Infrared sensor serves as a new tool for drug discovery

Scientists have found a new method for analysing how active agents affect a specific protein essential for cell survival. Their research could help to quickly develop drugs with fewer side effects.

Infrared sensor as new method for drug discovery

Using an infrared sensor, biophysicists at Ruhr-Universität Bochum (RUB) have succeeded in analysing quickly and easily which active agents affect the structure of proteins and how long that effect lasts. Thus, Prof Dr. ...

Plants feel the heat

It's not just humans and animals that suffer when the mercury rises, plants feel the heat too. Heat stress is a major issue in agriculture and can significantly reduce crop yield. Even small increases in temperature can affect ...

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