The genome is all about architecture

Many serious diseases such as malaria or AIDS present a major challenge for medicine because the causative pathogens use the same strategy although they are completely different: By camouflaging themselves they evade the ...

New studies explore 3-D structure of DNA

In a set of papers published last week in Cell Systems, Dr. Erez Lieberman Aiden, assistant professor of molecular and human genetics and McNair Scholar at Baylor College of Medicine and director of the Center for Genome ...

Stem cells know how to open up and unwind

Research led by the Babraham Institute with collaborators in the UK, Canada and Japan has revealed a new understanding of how an open genome structure supports the long-term and unrestricted developmental potential in embryonic ...

Protein factors tie the genome up in a bow for gene expression

Protein factors are responsible for organizing chromosomes inside the nucleus in three dimensions (3D), forming a shape like a gift bow, with proteins aggregating as the central 'knot' holding the ribbon-like loops of DNA ...

Genome duplication aids plant's survival in saline soils

(Phys.org) —Having more than two sets of chromosomes can increase a plant's ability to take up nutrients and survive in saline soils, a joint study by Purdue University and the University of Aberdeen shows.