New mouse model reveals a mystery of Duchenne muscular dystrophy

Children with Duchenne muscular dystrophy often die as young adults from heart and breathing complications. However, scientists have been puzzled for decades by the fact that laboratory mice bearing the same genetic mutation ...

Fast track to mouse modeling

What genes are responsible for the development of breast cancer? What are the brain cell mutations that lead to the onset of Alzheimer's? To find new therapies, scientists have to understand how diseases are triggered at ...

Autistic mice act a lot like human patients

UCLA scientists have created a mouse model for autism that opens a window into the biological mechanisms that underlie the disease and offers a promising way to test new treatment approaches.

Mouse genetic blueprint developed

Researchers have developed a valuable mouse genetic blueprint that will accelerate future research and understanding of human genetics. The international team, led by researchers at the Wellcome Trust Sanger Institute and ...

Aurora A may contribute to kidney disease

The Aurora A kinase may contribute to polycystic kidney disease (PKD) by inactivating a key calcium channel in kidney cells, according to a study in the June 13 issue of The Journal of Cell Biology.

The Nobel Prize and Pond Scum as a 'Model' Organism

A man is a man and a mouse is a mouse, but if you talk to a few biomedical scientists about their research, at least one is likely to spring the term “mouse model” on you.

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