Implications of no-free-lunch theorems

In the 18th century, the philosopher David Hume observed that induction—inferring the future based on what's happened in the past—can never be reliable. In 1997, SFI Professor David Wolpert with his colleague Bill Macready ...

3D-snapshots of nanoparticles

X-ray diffraction has been used for more than a hundred years to understand the structure of crystals or proteins—for instance, in 1952 the well-known double helix structure of the DNA that carries genetic information was ...

Predicting the evolution of genetic mutations

Quantitative biologists David McCandlish and Juannan Zhou at Cold Spring Harbor Laboratory have developed an algorithm with predictive power, giving scientists the ability to see how specific genetic mutations can combine ...

New algorithm rapidly finds anomalies in gene expression data

Computational biologists at Carnegie Mellon University have devised an algorithm to rapidly sort through mountains of gene expression data to find unexpected phenomena that might merit further study. What's more, the algorithm ...

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