During the first hours of an embryo's development, specialized molecules called pioneer transcription factors unravel parts of its DNA to activate the encoded genes. Which gene is activated and when has to follow a set schedule ...
Cell & Microbiology
Sep 28, 2023
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1
For decades, scientists have known that, despite its name, "junk DNA" in fact plays a critical role: While the coding genes provide blueprints for building proteins, which direct most of the body's functions, some of the ...
Biotechnology
Sep 27, 2023
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240
Tomato (Solanum lycopersicum), one of the most important horticultural crops, is rich in iron and vitamins. As an essential micro-element for plants, iron (Fe) deficiency not only restricts tomato growth, development and ...
Molecular & Computational biology
Sep 25, 2023
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1
In eukaryotes, genomic DNA, which is a very long double helix containing all the genetic information, wraps around a globular protein called a histone and folds it many times before being contained within the nucleus.
Molecular & Computational biology
Sep 22, 2023
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1
The intricate interplay of gene expression within living cells is akin to a well-orchestrated symphony, with each gene playing its part in perfect harmony to ensure cells function as they should. At the heart of this symphony ...
Cell & Microbiology
Sep 19, 2023
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135
In plants, 5mC DNA methylation is an important and conserved epistatic mark involving genomic stability, gene transcriptional regulation, developmental regulation, abiotic stress response, metabolite synthesis, etc. However, ...
Molecular & Computational biology
Aug 29, 2023
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15
A new study led by University of Maryland physicists sheds light on the cellular processes that regulate genes. Published in the journal Science Advances, the paper explains how the dynamics of a polymer called chromatin—the ...
Molecular & Computational biology
Aug 15, 2023
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11
Bioengineers can tailor the genomes of cells to create "cellular therapies" that fight disease, but they have found it difficult to design specialized activating proteins called transcription factors that can throw the switch ...
Cell & Microbiology
Aug 14, 2023
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1
New work by scientists in the U.S. and China shows how a fertilized egg cell, or zygote, hits "reset" so that the newly formed embryo can develop according to its own genetic program. The study was published July 17 in Nature.
Cell & Microbiology
Jul 20, 2023
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34
A new study by Rice University bioscientists explains how basic cellular structures common to most life forms collaborate to fuel growth in a model plant organism. The findings could shed light on corresponding mechanisms ...
Cell & Microbiology
Jul 13, 2023
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13
