A novel approach developed at the Friedrich Miescher Institute for Biomedical Research (FMI) has allowed scientists in Dirk Schübeler's group to dissect and quantify the individual steps of transcription initiation. Unexpectedly, ...
For the first time, a synthetic compound has been made that can bind to DNA in the cells' energy powerhouses, suppressing a gene associated with nerve and muscle disease.
UNC School of Medicine researchers have cracked a long-standing mystery about an important enzyme found in virtually all organisms other than bacteria. The basic science finding may have implications for understanding cancer ...
All animals—from sea sponges to modern-day humans—evolved in a world already teeming with microbes. These single-celled microorganisms now cover practically every surface of our bodies and are as much a part of our biology ...
The Arabidopsis thaliana is a tiny, inconspicuous and herbaceous offshoot of the family of cruciferous plant that one might easily overlook in a meadow, yet the plant has the potential to disrupt a common school of thought: ...
A new study in Science from Karolinska Institutet maps out how different DNA-binding proteins in human cells react to certain biochemical modifications of the DNA molecule. The scientists report that some 'master' regulatory ...
Single-celled plankton known as dinoflagellates are shown to cope with stress using an unexpected strategy of editing their RNA rather than changing gene expression levels.
(Phys.org)—An international team of researchers has found that gene transcription in an organism that has died continues for several days. In their paper published in the journal Royal Society Open Biology, the team describes ...
Researchers at the University of Wisconsin-Madison have developed a novel strategy to reprogram cells from one type to another in a more efficient and less biased manner than previous methods.
Substances known as transcription factors often determine how a cell develops as well as which proteins it produces and in what quantities. Transcription factors bind to a section of DNA and control how strongly a gene in ...
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