Related topics: gene expression

New compact model for gene regulation in higher organisms

Although the DNA and its double-helix are one of the most familiar molecules of our time, our knowledge of how cells control what genes they want to express is still rather limited. In order to create, for example, an enzyme, ...

The molecules responsible for transcriptional bursting

New insights into what causes neighboring, genetically identical stem cells in mouse embryos to behave differently in terms of the proteins they produce could have implications for regenerative medicine and the early detection ...

Human genetics: A look in the mirror

Who are we? Where did we come from? How did we get here? Throughout the ages, humans have sought answers to these questions, pursuing wisdom through religion, philosophy, and eventually science. Evolutionary analyses published ...

Proteins—and labs—coming together to prevent Rett syndrome

New discoveries about the disruption of condensates in the neurodevelopmental disorder Rett syndrome provide insights into how cells compartmentalize chromosomes as well as new potential paths for therapies.

Specialized cellular compartments discovered in bacteria

Researchers at McGill University have discovered bacterial organelles involved in gene expression, suggesting that bacteria may not be as simple as once thought. This finding could offer new targets for the development of ...

Researchers construct dynamic landscape of medaka embryogenesis

Medaka, a fish, has become an important vertebrate model widely used in genetics, developmental biology, environmental sciences, and many other fields. A high-quality genome sequence and a variety of genetic tools are available ...

A genome-scale map of DNA methylation kinetics

While the first genome-wide DNA methylation map in mammalian cells was established over 10 years ago, such maps only provide snapshots and do not inform about the actual dynamics of this epigenetic mark. Researchers from ...

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