A team led by Professor Virginijus Šikšnys from Vilnius University Life Sciences Center (VU LSC) determined the structure of TnpB using cryo-electron microscopy in collaboration with the group of Professor Guillermo Montoya ...
Cell & Microbiology
May 4, 2023
0
7
As genetic information carriers, nucleic acid molecules have been developed as gene therapeutic drugs. On the basis of complementary base pairing, nucleic acid can not only encode functional genes, but also precisely self-assemble ...
Bio & Medicine
Apr 25, 2023
0
38
Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of diseases. This has led to a growing demand for selective, efficient, and safe ways of delivering siRNA in cells. Now, in a cooperation ...
Bio & Medicine
Apr 19, 2023
0
47
Gene editing is one of the latest breakthroughs in biology. The widely known CRISPR-Cas gene editing system provided prokaryotes (organisms that lack cell nuclei) an immunity against foreign DNA. Since the discovery of the ...
Cell & Microbiology
Apr 7, 2023
0
56
The Okinawa Institute of Science and Technology (OIST), in collaboration with Astellas Pharma Inc., has developed a new toolkit that uses small molecules to control the activity of a piece of synthetic RNA, and ultimately ...
Biotechnology
Mar 30, 2023
0
155
University of Chicago scientists have discovered a new wrinkle in our understanding of how our genes work. The team, led by Chuan He, the UChicago John T. Wilson Distinguished Service Professor of Chemistry, Biochemistry ...
Molecular & Computational biology
Feb 13, 2023
0
731
Many life-saving drugs directly interact with DNA to treat diseases such as cancer, but scientists have struggled to detect how and why they work—until now.
Biotechnology
Jan 23, 2023
0
77
Gene therapies have the potential to treat neurological disorders like Alzheimer's and Parkinson's diseases, but they face a common barrier—the blood-brain barrier. Now, researchers at the University of Wisconsin-Madison ...
Bio & Medicine
Jan 19, 2023
0
114
Scientists have unlocked key insights into virus evolution, revealing new information that could help develop treatments for a wide variety of genetic diseases.
Evolution
Nov 30, 2022
0
100
The widely used gene scissor (CRISPR/Cas) can modify the genetic content in cells to study the molecular roles of genes and has gained great clinical relevance in gene therapy to treat genetic diseases. A new study performed ...
Biotechnology
Nov 14, 2022
0
108
