New understanding of CRISPR-Cas9 tool could improve gene editing

Within a mere eight years, CRISPR-Cas9 has become the go-to genome editor for both basic research and gene therapy. But CRISPR-Cas9 also has spawned other potentially powerful DNA manipulation tools that could help fix genetic ...

Simulations show how to make gene therapy more effective

Diseases with a genetic cause could, in theory, be treated by supplying a correct version of the faulty gene. However, in practice, delivering new genetic material to human cells is difficult. A promising method for the delivery ...

How do you weigh a single molecule?

Utrecht scientists have succeeded in measuring the mass of individual molecules. By modifying an existing mass spectrometer and developing special software, the researchers succeeded in making ultra-sensitive measurements. ...

Researchers plan DNA-based nanorobot for cancer diagnostics

A group of researchers from ITMO University has come up with the concept of a new drug against cancer: a nanorobot made of DNA fragments, which can potentially be used not only to destroy cancer cells, but also to locate ...

Exploring tiny forces with single molecule force spectroscopy

In terms of space organization, DNA has powers rivaling Marie Kondo. A strand of DNA that is two meters long intricately folds itself into a cell nucleus only 10 microns across. (One of the hairs on your head has a diameter ...

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