Related topics: genes

An 'oracle' for predicting the evolution of gene regulation

Despite the sheer number of genes that each human cell contains, these so-called "coding" DNA sequences comprise just 1% of our entire genome. The remaining 99% is made up of "non-coding" DNA—which, unlike coding DNA, does ...

The definitive guide to getting tall

There are many genes, or at least markers of one sort or another within our DNA sequences, that have been associated with height. By some estimates the number could be thousands. However, finding those select genes that have ...

New prime editing system inserts entire genes in human cells

Researchers at the Broad Institute of MIT and Harvard have developed a new version of prime editing that can install or swap out gene-sized DNA sequences. First developed in 2019, prime editing is a precise method of making ...

Machine learning discovers new sequences to boost drug delivery

Duchenne muscular dystrophy (DMD), a rare genetic disease usually diagnosed in young boys, gradually weakens muscles across the body until the heart or lungs fail. Symptoms often show up by age 5; as the disease progresses, ...

In situ sequencing of the fully structured genome

There is a sense in which the information encoded in a gene sequence can be represented by two bits per base pair location. The reality, however, is that this is far from a complete description. Although many academically ...

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