CRISPR-Cas9 is the go-to technique for knocking out genes in human cell lines to discover what the genes do, but the efficiency with which it disables genes can vary immensely.
Biotechnology
Aug 17, 2016
0
172
Despite the sheer number of genes that each human cell contains, these so-called "coding" DNA sequences comprise just 1% of our entire genome. The remaining 99% is made up of "non-coding" DNA—which, unlike coding DNA, does ...
Molecular & Computational biology
Mar 9, 2022
2
268
For most of our evolutionary history—for most of the time anatomically modern humans have been on Earth—we've shared the planet with other species of humans. It's only been in the last 30,000 years, the mere blink of ...
Archaeology
Dec 19, 2019
6
3116
It's one of the greatest mysteries of modern science: how did life begin exactly? While most scientists believe that all lifeforms evolved from a common, primitive ancestor microorganism, the details are blurry. What kinds ...
Cell & Microbiology
Jul 26, 2016
20
1975
The Y chromosome may be a symbol of masculinity, but it is becoming increasingly clear that it is anything but strong and enduring. Although it carries the "master switch" gene, SRY, that determines whether an embryo will ...
Evolution
Jul 13, 2020
0
627
A team of Johns Hopkins University researchers has developed a new software that could revolutionize how DNA is sequenced, making it far faster and less expensive to map anything from yeast genomes to cancer genes.
Biotechnology
Dec 3, 2020
0
1167
How did the monstrous giant squid—reaching school-bus size, with eyes as big as dinner plates and tentacles that can snatch prey 10 yards away—get so scarily big?
Biotechnology
Jan 16, 2020
0
2197
Charles Darwin's Theory of Evolution, first published in 1859, offered a bold new explanation for how animals and plants diversified and still serves as the foundation underpinning all medical and biological research today. ...
Evolution
Sep 11, 2014
124
0
A study investigating samples of the superbug Clostridioides difficile across 14 pig farms in Denmark finds the sharing of multiple antibiotic-resistance genes between pigs and human patients, providing evidence that that ...
Diseases, Conditions, Syndromes
Apr 24, 2022
0
72
After extracting ancient DNA from the 40,000-year-old bones of Neanderthals, scientists have obtained a draft sequence of the Neanderthal genome, yielding important new insights into the evolution of modern humans.
Evolution
May 6, 2010
63
2
