Gene mutation that makes dogs small existed in ancient wolves

Popular belief has been that small dogs, such as Pomeranians and Chihuahuas, exist because once dogs were domesticated, humans wanted small, cute companions. But in the journal Current Biology on January 27, researchers at ...

Machine learning discovers new sequences to boost drug delivery

Duchenne muscular dystrophy (DMD), a rare genetic disease usually diagnosed in young boys, gradually weakens muscles across the body until the heart or lungs fail. Symptoms often show up by age 5; as the disease progresses, ...

A comprehensive map of the SARS-CoV-2 genome

In early 2020, a few months after the Covid-19 pandemic began, scientists were able to sequence the full genome of the virus that causes the infection, SARS-CoV-2. While many of its genes were already known at that point, ...

Testing the 'two-hit' model for developmental defects

A mutation that deletes a large segment of human chromosome 16 and is associated with neurodevelopmental disorders doesn't work alone. A new functional assay demonstrates how the deletion could be sensitizing the genome such ...

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