New method melds data to make a 3-D map of cells' activities

Just as it's hard to understand a conversation without knowing its context, it can be difficult for biologists to grasp the significance of gene expression without knowing a cell's environment. To solve that problem, researchers ...

Supercomputers reveal how X chromosomes fold, deactivate

Using supercomputer-driven dynamic modeling based on experimental data, researchers can now probe the process that turns off one X chromosome in female mammal embryos. This new capability is helping biologists understand ...

A Swiss army knife for genomic data

A good way to find out what a cell is doing—whether it is growing out of control as in cancers, or is under the control of an invading virus, or is simply going about the routine business of a healthy cell—is to look ...

At the core of the integrator complex

Gene expression is a highly regulated process that involves several steps. These include transcription of DNA instructions into RNA, removal of non-coding segments from the RNA message, and its subsequent translation into ...

A one-stop shop for analyzing algal genomes

Interested in the genomes of algae? You now have one place where you can browse the genetic blueprints of these photosynthetic organisms. PhycoCosm is one of the largest data repositories of its kind, with an interactive ...

How maize makes an antibiotic cocktail

Maize (Zea mays) produces a plethora of antibiotics called zealexins. Even though scientists have identified at least 15 zealexins, they suspect there are even more to find. Zealexins are produced in every corn variety and ...

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