Scientists have developed a new technique to accelerate the discovery of cancer-fighting drugs. The technique identifies molecules that can shut down dangerous proteins before they wreak disease-triggering havoc, by blocking ...
Biochemistry
Apr 7, 2022
0
85
Developing drugs to combat tuberculosis, or TB, can be frustrating business. A gene essential to the bacteria's lifecycle is discovered, scientists rush to develop drugs that inhibit the target, and then—disappointment. ...
Molecular & Computational biology
Jul 23, 2021
0
189
Researchers at the University of Pennsylvania School of Veterinary Medicine (Penn Vet) have successfully developed a new test to systemically detect the local administration of illicit, gene doping therapies in equine athletes. ...
Biotechnology
Mar 10, 2021
0
12
In an effort to address a major challenge when analyzing large single-cell RNA-sequencing datasets, researchers from The University of Texas MD Anderson Cancer Center have developed a new computational technique to accurately ...
Biotechnology
Jan 18, 2021
0
45
Researchers from Boston University School of Medicine (BUSM) have developed and implemented a new way to better understand how human cells communicate with each other, how this communication is disrupted in human diseases ...
Biotechnology
Jul 6, 2020
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40
Johns Hopkins researchers have discovered a long-sought protein, the proton-activated chloride channel (PAC), that is activated in acidic environments and could protect against the tissue-damaging effects of stroke, heart ...
Evolution
May 20, 2019
0
13
Vampire bats could hold the key to new treatments for a range of serious medical problems, but researchers have hit a snag accessing the specimens needed to advance their work.
Biochemistry
Jan 15, 2019
0
20
Regulation of gene expression—turning genes on or off, increasing or decreasing their expression—is critical for defining cell identity during development and coordinating cellular activity throughout the cell's lifetime. ...
Cell & Microbiology
Nov 19, 2018
0
70
In 2013, Broad Institute member Cigall Kadoch, then a postdoctoral researcher at Stanford University, discovered that approximately 20 percent of all human cancers involve mutations in a group of proteins called BAF, a complex ...
Cell & Microbiology
Oct 22, 2018
0
18
Researchers at the Broad Institute of MIT and Harvard have taken the Connectivity Map—a widely used resource of tools and data—to new heights with a massively scaled-up version. For this new platform, the researchers ...
Biotechnology
Nov 30, 2017
0
5
