A new class of medicinal compounds that target RNA

A team of undergraduate and graduate chemistry students in Jennifer Hines' lab at Ohio University recently uncovered a new class of compounds that can target RNA and disrupt its function. This discovery identified a chemical ...

Glowing tags reveal split-second activity of pathogenic circuitry

Synthetic biologists at Rice University have developed the first technology for observing the real-time activity of some of most common signal-processing circuits in bacteria, including deadly pathogens that use the circuits ...

An inexpensive resource for the protein-research community

Labs can easily make their own protein ladders—molecular rulers for estimating the sizes of proteins—for less than a penny per experiment using the newly developed, license-free "Penn State Protein Ladder system." A ...

Finding a handle to bag the right proteins

Purifying specific protein molecules from complex mixtures will become easier with a simpler way to detect a molecular tag commonly used as a handle to grab the proteins.

To improve health monitoring, simply trip the 'nanoswitch'

Engineered strands of DNA—nanoscale tools called "nanoswitches"—could be the key to faster, easier, cheaper and more sensitive tests that can enable high-fidelity detection of biomarkers indicating the presence of different ...

Stiffening the backbone of DNA nanofibers

An international collaboration including researchers from the NIST Center for Nanoscale Science and Technology and the Universidad San Francisco de Quito, Ecuador have fabricated a self-assembled nanofiber from a DNA building ...

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