Readers of the top-ranked scientific journals Science and Nature might have noticed a recent wave of articles, most recently in the July 13, 2012 issue of Science, with deep importance for biology and medicine. These papers, ...
Cell & Microbiology
Jul 12, 2012
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Researchers have developed a light-activated tool to show how drugs need to be adapted to combat type 2 diabetes.
Biochemistry
Apr 11, 2016
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30
Researchers hope to design a new generation of drugs against an array of deadly diseases. The task, however, is costly, arduous and often ineffective. One of the key challenges is understanding a particular class of proteins ...
Biochemistry
Apr 5, 2017
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109
There is a large, untapped potential for developing drugs against cancer, fibrosis and cardiovascular diseases by targeting a family of receptors known as Frizzleds, researchers at Karolinska Institutet in Sweden believe. ...
Biochemistry
Dec 4, 2018
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71
Last year's Nobel Prize in Chemistry – shared by Stanford School of Medicine Professor Brian Kobilka and Robert Lefkowitz of Duke University – recognized groundbreaking research in G protein-coupled receptors (GPCRs). ...
General Physics
May 10, 2013
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About 30 percent of the proteins encoded by the human genome are membrane proteins—proteins that span the cell membrane so they can facilitate communication between cells and their environment. These molecules are critical ...
Biochemistry
Aug 28, 2018
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110
In November 2017, a Titan Krios cryo-electron microscope (cryo-EM) was inaugurated at the ESRF, the European Synchrotron, France. Data collected on this cryo-EM features in a Nature publication describing the activation cycle ...
Biochemistry
Oct 31, 2018
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22
There are a number of G protein-coupled receptors in human cells. As an important component of the cell membrane, these proteins are responsible for detecting different stimuli in the surroundings of a cell within the body ...
Biochemistry
Oct 25, 2021
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117
For the first time, scientists have visualized the interaction between two critical components of the body's vast cellular communication network, a discovery that could lead to more effective medications with fewer side effects ...
Biochemistry
Jun 13, 2018
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24
G protein-coupled receptors (GPCRs) are the largest class of cell surface receptors in our cells, involved in signal transmission across the cell membrane. One of the biggest questions is how a signal recognized at the extracellular ...
Cell & Microbiology
Sep 9, 2014
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