Big data kinase ohmics takes over drug discovery

In order for tumors to successfully take hold and spread in the body, they typically must meet several developmental milestones. These include things like suppressing apoptosis, cultivating replication and angiogenesis, weaning ...

Laser pulses reveal DNA repair mechanisms

A new straightforward method enables monitoring the response of nuclear proteins to DNA damage in time and space. The approach is based on nonlinear photoperturbation.

Driving membrane curvature

(Phys.org) -- In biological systems, membranes are as important as water. They form the barrier between the inner world, within our cells, where we perform the chemical reactions of life, and the outside environment.

Slow-release 'jelly' delivers peptide drugs better

Duke University biomedical engineers have developed a new delivery system that overcomes the shortcomings of a promising class of peptide drugs – very small proteins – for treating diseases such as diabetes and cancer.

Membrane fusion a mystery no more

The many factors that contribute to how cells communicate and function at the most basic level are still not fully understood, but researchers at Baylor College of Medicine have uncovered a mechanism that helps explain how ...

Research team achieves first 2-color STED microscopy of living cells

Researchers are able to achieve extremely high-resolution microscopy through a process known as stimulated emission depletion (STED) microscopy. This cutting-edge imaging system has pushed the performance of microscopes significantly ...

Cell death pathway linked to mitochondrial fusion

New research led by UC Davis scientists provides insight into why some body organs are more susceptible to cell death than others and could eventually lead to advances in treating or preventing heart attack or stroke.

New clues about mitochondrial 'growth spurts'

Mitochondria are restless, continually merging and splitting. But contrary to conventional wisdom, the size of these organelles depends on more than fusion and fission, as Berman et al. show. Mitochondrial growth and degradation ...

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