Anticancer mechanism revealed in yeast experiments

Much like shoelaces or dangly necklaces, DNA strands can tangle up in unruly knots. Specialized enzymes keep DNA organized when cells divide, so the cells split smoothly and don't get stuck. But in tumor cells, this failsafe ...

How sex pheromones diversify: Lessons from yeast

Many organisms including insects, amphibians and yeasts use sex pheromones for attracting individuals of the opposite sex, but what happens to sex pheromones as new species emerge? New research publishing January 22 in the ...

Evolutionarily conserved enzyme play key role in DNA replication

Genome-wide studies of fission yeast (Schizosaccharomyces pombe) suggest that the evolutionary conserved enzyme Pfh1 helicase facilitates DNA synthesis by tracking along with the replication apparatus, promoting intact DNA ...

Cellular memory of stressful situations

Stress is unhealthy. The cells use therefore a variety of mechanisms to deal with stress and avert its immediate threat. However, certain stressful situations leave marks that go beyond the immediate response; some even seem ...

Imaging the genome: Cataloguing the fundamental processes of life

The team of researchers, led by Dr Rafael Carazo Salas from the Department of Genetics, combined high-resolution 3D confocal microscopy and computer-automated analysis of the images to survey the fission yeast genome with ...

Brewing yeasts reveal secrets of chromosomal warfare and dysfunction

Using two yeasts that have been used to brew tea and beer for centuries, researchers at Fred Hutchinson Cancer Research Center have revealed how reproductive barriers might rapidly arise to create species boundaries. Schizosaccharomyces ...

Biologists identify proteins vital to chromosome segregation

New York University biologists have identified how a vital protein is loaded by others into the centromere, the part of the chromosome that plays a significant role in cell division. Their findings shed new light on genome ...

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