Collagen fibres grow like a sunflower

Collagen fibrils are a major component of the connective tissues found throughout the animal kingdom. The cable-like assemblies of long biological molecules combine to form tissues as varied as skin, corneas, tendons or bones. ...

Technique uses well-known dye to watch amyloid plaques in the brain

While amyloid plaques have long been closely associated with mechanisms driving Alzheimer's disease, visualizing how amyloid proteins assemble continues to prove difficult. The nanometer-sized amyloid fibrils are only a fraction ...

A boundary dance of amyloid-β stepping into dementia

Alzheimer's disease is caused by aggregates of amyloid-β (Aβ) peptides. This aggregation is accelerated at the cell membrane surface. Using molecular dynamics simulations and NMR experiments, the research group at ExCELLS ...

Algorithmic innovation may help reduce invasive heart procedures

Doctors use invasive procedures to map the hearts of patients suffering from atrial fibrillation, an abnormal heart rhythm, to decide whether an ablation procedure to remove heart tissue is likely to have a positive outcome. ...

Parkinson-related protein is 'tunable'

Fibrils of the protein alpha-synuclein, that plays a role in Parkinson's disease, form a stiffer and stronger network in water, when temperature is increased. Researchers of the University of Twente show that this has to ...

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