Related topics: cancer cells

Transformer cells: Shaping cellular 'behaviour'

Scientists from Sechenov University, conjointly with their fellow Chinese and American researchers, have examined the latest advances in the use of skeletal muscle progenitor cells, specifying the core challenges inherent ...

Partial mechanical unfolding may regulate protein function

A study carried out as a collaborative approach between University of Tampere, Finland, and Imperial College London has shown that mechanically regulated proteins talin and α-catenin have stable intermediates during mechanical ...

Ionizing radiation found to soften tumor cell microenvironment

Nearly half of all cancer patients receive radiation therapy to curb the growth of malignant cells. But little is known about how ionizing radiation affects the extracellular matrix (ECM), a patchwork of proteins and other ...

Bridging tumor moats with potent drug delivery particles

Despite herculean efforts, cancer remains a formidable disease, with each malignant subtype responding differently to therapeutics. One hurdle specific to treating solid tumors is a protective layer called an extracellular ...

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Extracellular matrix

In biology, the extracellular matrix (ECM) is the extracellular part of animal tissue that usually provides structural support to the animal cells in addition to performing various other important functions. The extracellular matrix is the defining feature of connective tissue in animals.

Extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.

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