Related topics: cancer cells

Genomic secrets of gutless deep-sea tubeworm unlocked

Researchers from The Hong Kong University of Science and Technology (HKUST) decoded for the first time the chromosomal-level genome of a deep-sea gutless tubeworm and how the worm's co-living bacterial partners manufacture ...

Basement membrane underpins tissue interactions in the skin

In a discovery that could pave the way for therapies that promote wound healing and alleviate skin diseases, RIKEN researchers have found that the network of molecules under the outermost layer of mouse skin, the skin epithelium, ...

Watch immune cells dig tunnels in tissues

White blood cells called cytotoxic T lymphocytes (CTLs) dig tunnels in tissues, potentially allowing other CTLs to quickly reach infected cells and tumor cells, researchers report December 1st in Biophysical Journal. The ...

Researchers elucidate the mechanics of cellular attachment

For cells to assemble into tissues and whole organs, the extracellular matrix (ECM) as well as integrins are required. The ECM forms a kind of extra-cellular protein meshwork; the integrins are surface proteins, which cells ...

Nanomotors as probes to sense cancer environment

An interdisciplinary team of researchers from the Indian Institute of Science (IISc) has used a 3-D tumor model and magnetically driven nanomotors to probe the microenvironment of cancer cells. The team consists of researchers ...

Researchers study a novel type of extracellular vesicles

Researchers from Sechenov University and the University of Pittsburgh compared the properties of two groups of extracellular vesicles. Either present in a liquid phase or attached to the fibres of the extracellular matrix, ...

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Extracellular matrix

In biology, the extracellular matrix (ECM) is the extracellular part of animal tissue that usually provides structural support to the animal cells in addition to performing various other important functions. The extracellular matrix is the defining feature of connective tissue in animals.

Extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.

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