A new study led by ISGlobal and IGTP uses a mouse model with human liver cells to characterize proteins associated with the latent form of the malaria parasite Plasmodium vivax. The findings lay the groundwork for identifying ...
Cell & Microbiology
Nov 8, 2022
0
3
A new paper in Cell Systems explores the importance of using multiple data types in drug discovery. The paper screens more than 1,000 drugs tested in six doses and demonstrates that gene expression and cell morphology provide ...
Cell & Microbiology
Oct 24, 2022
0
4
Bacteria and other unicellular organisms developed sophisticated ways to actively navigate their way, despite being comparably simple structures. To reveal these mechanisms, researchers from the Max Planck Institute for Dynamics ...
Cell & Microbiology
Aug 1, 2022
0
18
The chemical industry has only scratched the surface of possible molecules that could be used as drugs, which is unimaginably greater than the number of stars in the universe. To make navigating this vast chemical space more ...
Other
Jun 30, 2022
0
12
As the opioid epidemic raged on with an even greater force during COVID-19, the Scripps Research laboratory of chemist Kim Janda, Ph.D., has been working on new therapeutic interventions that may be able to prevent the bulk ...
Biochemistry
Feb 4, 2021
1
653
Published in Nature Physics, findings from a new study co-led by Cleveland Clinic and Case Western Reserve University teams show for the first time how ideas from quantum physics can help develop novel drug interventions ...
General Physics
Aug 24, 2020
0
446
Lawrence Livermore National Laboratory (LLNL) scientists are contributing to the global fight against COVID-19 by combining artificial intelligence/machine learning, bioinformatics and supercomputing to help discover candidates ...
Biotechnology
Mar 25, 2020
0
22
Proteins that contain metal, known as metalloproteins, play important roles in biology, regulating various pathways in the body, which often become targets for lifesaving drugs. While the amount of metal in such proteins ...
Biochemistry
Jan 22, 2020
0
33
Scientists at the National Research Nuclear University MEPhI (MEPhI) have studied the optical properties of detonation nanodiamonds when interacting with various biomacromolecules (biopolymer molecules).
Optics & Photonics
Oct 7, 2019
0
16
Twenty years ago, scientists and investors were giddy over the promise of gene therapy to cure a host of deadly diseases. But the tragic death of a young man from an experimental treatment in 1999 nearly ended a scientist's ...
Other
Sep 18, 2019
0
4
An experimental drug is a substance that has been tested in a laboratory and has got approval from regulatory authorities to be tested in people. In the United States, the body responsible for approval is the U.S. Food and Drug Administration (FDA). A drug may be approved for use in one disease or condition but be considered experimental or investigational in other diseases or conditions.
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