How the antibiotic chloramphenicol causes damage to eukaryotes

A group of scientists from Japan led by Professor Takashi Kamakura of Tokyo University of Science has demonstrated the molecular and cellular basis of the toxic effects of the antibiotic chloramphenicol on eukaryotic cells. ...

Nuclear pore complex outer rings: No longer 'one size fits all'

In eukaryotic cells, the nucleus is walled off from the rest of the cell by the nuclear envelope. All transport into and out of the nucleus occurs via cylindrical channels called nuclear pore complexes (NPCs) that penetrate ...

Biochemists untangle mysteries of cellular form, function

The complex inner workings of cells, from their architecture to their signaling, underlie much of multicellular organic life. How are they built? How do their proteins interact? And most crucially, how can understanding these ...

A solid scaffolding for cells

To perform the task for which they have been synthesized, proteins must first assemble to form effective cellular "machines." But how do they recognize their partners at the right time? Researchers at the University of Geneva ...

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