A new molecular guardian of intestinal stem cells

Intestinal stem cells hold a fine balance between two potential forms: remaining as stem cells, or developing into intestinal epithelial cells. In a new study, researchers from Tokyo Medical and Dental University (TMDU) discovered ...

Catch and release: Collagen-mediated control of PEDF availability

Cells are like tiny self-contained machines that are constantly fine-tuned in response to both internal and external signals. Some of these signals are induced by extracellular ligands, specialized proteins that bind to specific ...

Advancing the science of smell—with a hint of musk

Researchers have identified key molecular mechanisms at work when people smell musks, a highly valued group of fixatives used in many perfumes and colognes. The discovery may have implications for a wide range of effects ...

Intestinal cells stave off bacteria by purging

Though purging is not prescribed as often as it was centuries ago, intestinal cells known as enterocytes frequently resort to this age-old remedy. Researchers from the Immune Response and Development in Insects (CNRS), Molecular ...

Molecular docking site of a bacterial toxin identified

Clostridium difficile is a dangerous intestinal bacterium that can cause severe diarrhoea and life-threatening intestinal infections after long-term treatment with antibiotics. The pharmacologists and toxicologists Prof. ...

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Epithelium

Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue. Epithelial tissues line the cavities and surfaces of structures throughout the body, and also form many glands. Functions of epithelial cells include secretion, selective absorption, protection, transcellular transport and detection of sensation. In Greek "Epi" means, "on, upon," and "Theli" meaning "tissue." Epithelial layers are avascular, so they must receive nourishment via diffusion of substances from the underlying connective tissue, through the basement membrane.[unreliable source?] Epithelia can also be organized into clusters of cells that function as exocrine and endocrine glands. Exocrine and endocrine epithelial cells are highly vascular.

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