Related topics: cells · cancer cells · protein

Simple bioreactor makes 'gut check' more practical

Rice University and Baylor College of Medicine researchers have found a way to mimic conditions in intestines, giving them a mechanical model for the real-time growth of bacterial infections.

Decoded: The structure of the barrier between three cells

Organs in animals and in humans have one thing in common: they are bounded by so-called epithelial cells. These, along with the muscle, connective and nervous tissues, belong to the basic types of tissue. Epithelial cells ...

A new molecular guardian of intestinal stem cells

Intestinal stem cells hold a fine balance between two potential forms: remaining as stem cells, or developing into intestinal epithelial cells. In a new study, researchers from Tokyo Medical and Dental University (TMDU) discovered ...

A new view on how tissues flow in the embryo

As embryos develop, tissues flow and reorganize dramatically on timescales as brief as minutes. This reorganization includes epithelial tissues that cover outer surfaces and inner linings of organs and blood vessels. As the ...

Using alveolar epithelia as a model for coronavirus infection

Before new drugs can be administered to people, researchers first have to investigate their effects using cell cultures and animal testing. Human cell cultures are increasingly being used as a model system for this purpose. ...

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Epithelium

In biology and medicine, an epithelium is a tissue composed of cells that line the cavities and surfaces of structures throughout the body. Many glands are also formed from epithelial tissue. It lies on top of connective tissue, and the two layers are separated by a basement membrane.

In humans, epithelium is classified as a primary body tissue, the other ones being connective tissue, muscle tissue and nervous tissue.

Epithelium is often defined by the expression of the adhesion molecule e-cadherin (as opposed to n-cadherin, which is used by cells of the connective tissue).

Functions of epithelial cells include secretion, selective absorption, protection, transcellular transport and detection of sensation and they commonly as a result present extensive apical-basolateral polarity (e.g. different membrane proteins expressed) and specialisation.

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