Related topics: protein · cells · bacteria · chemical reactions · cancer

AI heralds new frontiers for predicting enzyme activity

Researchers from the Departments of Chemistry and Engineering Science at the University of Oxford have found a general way of predicting enzyme activity. Enzymes are the protein catalysts that perform most of the key functions ...

Next step on the path towards an efficient biofuel cell

Fuel cells that work with the enzyme hydrogenase are, in principle, just as efficient as those that contain the expensive precious metal platinum as a catalyst. However, the enzymes need an aqueous environment, which makes ...

Fully identified—the pathway of protons

In their catalytic center, hydrogenases manufacture molecular hydrogen (H2) from two protons and two electrons. They extract the protons required for this process from the surrounding water and transfer them – via a transport ...

Metallic nanocatalysts imitate the structure of enzymes

An international team of researchers has transferred certain structural characteristics of natural enzymes, which ensure particularly high catalytic activity, to metallic nanoparticles. The desired chemical reaction thus ...

Disrupting communication in infectious bacteria

Chemists in Konstanz have inhibited the biosynthesis of a bacterial signal and, as a result, blocked the infectious properties of Pseudomonas aeruginosa, the most common germ found in health care facilities.

External structure can affect the function of enzymes

A research team from Ruhr-Universität Bochum (RUB) and from South Africa has analysed two enzymes with identical substrate binding pockets that nevertheless convert different substrates. In the process, it emerged that changes ...

Heat-resistant enzymes could produce more cost-effective drugs

A new study published in Proceedings of the National Academy of Sciences could change the way scientists look at one of the most essential enzymes in medicine in hopes of designing better and more cost-effective drugs in ...

Gut bacteria influence movement in flies

Warm, protected, and full of nutrients—the tiny intestines of a fruit fly are a perfect habitat for some bacteria. These bacteria, in turn, help the fly break down and digest food, keeping the insect's metabolism running ...

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