Blue light: An on-off switch for enzymes

Light affects living organisms in many different ways, for example, plants orient their growth direction towards the sun, while circadian rhythms in humans are controlled by daylight. These processes always involve photoreceptors, ...

Nanosensors target enzymes to monitor and study cancer

Cancer is characterized by a number of key biological processes known as the "hallmarks of cancer," which remodel cells and their immediate environment so that tumors can form, grow, and thrive. Many of these changes are ...

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Enzyme catalysis

Enzyme catalysis is the catalysis of chemical reactions by specialized proteins known as enzymes. Catalysis of biochemical reactions in the cell is vital due to the very low reaction rates of the uncatalysed reactions.

The mechanism of enzyme catalysis is similar in principle to other types of chemical catalysis. By providing an alternative reaction route and by stabilizing intermediates the enzyme reduces the energy required to reach the highest energy transition state of the reaction. The reduction of activation energy (ΔG) increases the number of reactant molecules with enough energy to reach the activation energy and form the product.

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