To successfully engineer cell or tissue implants, bioengineers must facilitate their metabolic requirements through vascular regeneration. However, it is challenging to develop a broad strategy for stable and functional vascularization. ...
In a new report published on Scientific Reports, Michael J. Rupar, and a research team at Hesperos Inc., Florida, U.S., developed a functional, multi-organ, serum-free system to culture P. falciparum—a protozoan that predominantly ...
Research led by the University of Pennsylvania, Philadelphia, has used siRNA-based silencing of protein cyclophilin A (CyPA) to reduce tumor burden and extend the lives of patients with multiple myeloma.
Research in animal models has demonstrated that stem-cell derived heart tissues have promising potential for therapeutic applications to treat cardiac disease. But before such therapies are viable and safe for use in humans, ...
Bio & Medicine
Mar 8, 2023
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40
Transposable elements, or jumping genes, are now known to be responsible for many human diseases. Keeping them repressed by methylation, RNA binding, or the attentions of the innate immune system is a full-time jump for ...
During the progression of pulmonary hypertension, structural and functional changes in the small muscular arteries play a significant role and contribute to the disease. Bioengineers aim to develop advanced, anatomically ...
A scrupulous gatekeeper stands between the brain and its circulatory system to let in the good and keep out the bad, but this porter, called the blood-brain barrier, also blocks trial drugs to treat diseases like Alzheimer's ...
Bio & Medicine
Feb 10, 2020
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615
RNA interference (RNAi), a technique that can turn off specific genes inside living cells, holds great potential for treating many diseases caused by malfunctioning genes. However, it has been difficult for scientists to ...
Bio & Medicine
May 12, 2014
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0
A new bioprinting method developed at the Wyss Institute for Biologically Inspired Engineering at Harvard University and the Harvard School of Engineering and Applied Sciences (SEAS) creates intricately patterned 3D tissue ...
Materials Science
Feb 19, 2014
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0
Nearly 70 percent of patients with advanced breast cancer experience skeletal metastasis, in which cancer cells migrate from a primary tumor into bone—a painful development that can cause fractures and spinal compression. ...
Analytical Chemistry
Feb 6, 2014
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1
The endothelium is the thin layer of cells that line the interior surface of blood vessels, forming an interface between circulating blood in the lumen and the rest of the vessel wall. Endothelial cells line the entire circulatory system, from the heart to the smallest capillary. These cells reduce turbulence of the flow of blood allowing the fluid to be pumped farther.
Endothelial tissue is a specialized type of epithelium tissue (one of the four types of biological tissue in animals). More specifically, it is simple squamous epithelium.
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