How stem cells self-organize in the developing embryo

Embryonic development is a process of profound physical transformation, one that has challenged researchers for centuries. How do genes and molecules control forces and tissue stiffness to orchestrate the emergence of form ...

The source of stem cells points to two proteins

Mammalian embryos are unlike those of any other organism as they must grow within the mother's body. While other animal embryos grow outside the mother, their embryonic cells can get right to work accepting assignments, such ...

Honeybee protein keeps stem cells youthful

An active protein component of royal jelly helps honeybees create new queens. Stanford researchers have identified a similar protein in mammals, which keeps cultured embryonic stem cells pluripotent.

Maintaining the unlimited potential of stem cells

Embryonic stem cells (ESCs) are the very definition of being full of potential, given that they can become any type of cell in the body. Once they start down any particular path toward a type of tissue, they lose their unlimited ...

Team uncovers the underlying mechanisms of 3-D tissue formation

If you want to build an organ for transplant, you need to think in 3-D. Using stem cells, scientists are now able to grow parts of organs in the lab, but that is a far cry from constructing a fully-formed, functioning, three-dimensional ...

Stem cells organize themselves into pseudo-embryos

The definitive architecture of the mammalian body is established shortly after implantation of the embryo in the uterus. The antero-posterior, dorso-ventral and medio-lateral axes of the body become organized under the control ...

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