When it comes to chemical reactions, fluorine has a reputation as a 'magic bullet atom' for its ability to increase a drug's absorption and prolong its lifetime. However, traditional methods of adding it to compounds entail ...
Biochemistry
Nov 13, 2023
0
16
Under the ocean's surface, marine organisms are constantly releasing invisible molecules. Some of the chemical clues reveal which creatures are nearby, while others could be used someday as medications.
Biochemistry
Nov 8, 2023
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4
For years, if you asked the people working to create new pharmaceutical drugs what they wished for, at the top of their lists would be a way to easily replace a carbon atom with a nitrogen atom in a molecule.
Analytical Chemistry
Nov 1, 2023
1
1419
A detailed atomic exploration into how the dengue virus replicates its genome could catalyze the development of high-precision targeted antiviral therapeutics.
Cell & Microbiology
Oct 31, 2023
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1
One double-helix strand of DNA could extend six feet, but it is so tightly coiled that it packs an entire sequence of nucleotides into the tiny nucleus of a cell. If that same DNA was instead split into two strands and divided ...
Biotechnology
Oct 17, 2023
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85
The genome of the SARS-CoV-2 virus encodes 29 proteins, one of which is an ion channel called E. This channel, which transports protons and calcium ions, induces infected cells to launch an inflammatory response that damages ...
Biochemistry
Oct 13, 2023
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56
Most drugs are small molecules that bind firmly to a specific target—some molecule in human cells that is involved in a disease—in order to work. For example, a cancer drug's target might be a molecule that is abundant ...
Biochemistry
Sep 29, 2023
0
59
Boosting virtual screening with machine learning allowed for a 10-fold time reduction in the processing of 1.56 billion drug-like molecules. Researchers from the University of Eastern Finland teamed up with industry and supercomputers ...
Analytical Chemistry
Sep 22, 2023
0
18
Separating molecules is critical to producing many essential products. For example, in petroleum refining, the hydrocarbons—chemical compounds composed of hydrogens and carbons—in crude oil are separated into gasoline, ...
Materials Science
Sep 10, 2023
2
110
Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge. Now, researchers at Weill Cornell Medicine and RMIT ...
Biochemistry
Aug 31, 2023
0
8
