Engineered E. coli produces high levels of D-ribose

D-ribose is a commercially important sugar used as a sweetener, a nutritional supplement, and as a starting compound for synthesizing riboflavin and several antiviral drugs. Genetic engineering of Escherichia coli to increase ...

Blocking the active site of thiolase

Scientists at the University of Oulu, Finland, and at the Helmholtz Center Berlin (HZB) have shown the way to new directions in drug development against African sleeping sickness and other tropical parasitic infections. This ...

A protein provides stress relief for cells

German researchers have shown a new mechanism via which cells defend themselves against stress. Dr. Kathrin Thedieck and Birgit Holzwarth from the Institute of Biology III and the Cluster of Excellence BIOSS Centre for Biological ...

Cells control energy metabolism via hedgehog signalling pathway

Cancer, diabetes, and excess body weight have one thing in common: they alter cellular metabolism. Scientists from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and the Medical University of Vienna ...

Reversible method of tagging proteins developed

Chemists at UC San Diego have developed a method that for the first time provides scientists the ability to attach chemical probes onto proteins and subsequently remove them in a repeatable cycle.

How does body temperature reset the biological clock?

Numerous processes in our body fluctuate in a regular pattern during the day. These circadian (or daily) variations can be driven by local oscillators present within our cells or by systemic signals controlled by the master ...

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