Molecular simulations show how drugs block key receptors

Many pharmaceuticals work by targeting what are known as 'G-protein-coupled receptors.' In a new study, scientists from Uppsala University describe how they have been able to predict how special molecules that can be used ...

New macrolactone database could aid drug discovery, research

Researchers from North Carolina State University and Collaborations Pharmaceuticals have created a free-to-use database of 14,000 known macrolactones—large molecules used in drug development—which contains information ...

Biochemists trap and visualize an enzyme as it becomes active

How do you capture a cellular process that transpires in the blink of an eye? Biochemists at MIT have devised a way to trap and visualize a vital enzyme at the moment it becomes active—informing drug development and revealing ...

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