A collaborative effort has revealed a new type of triterpene, a group of organic compounds which are an important source of many medicines. Until now, all triterpenes were believed to be derived from squalene, itself a type ...
Biochemistry
Jun 1, 2022
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140
(Phys.org)—Drug design involves guided trial-and-error. How the body metabolizes a particular drug is important for determining drug efficacy. There have been many studies to understand how xenobiotics interact with cytochrome ...
A team of Yale University scientists has synthesized for the first time a chemical compound called lomaiviticin aglycon, leading to the development of a new class of molecules that appear to target and destroy cancer stem ...
Biochemistry
Jan 31, 2011
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0
Using electricity, a new method offers the possibility of recycling CO2 while also performing a notoriously difficult reaction, producing compounds potentially useful for drug development.
Analytical Chemistry
Feb 22, 2022
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88
A new automated workflow developed by scientists at Lawrence Berkeley National Laboratory (Berkeley Lab) has the potential to allow researchers to analyze the products of their reaction experiments in real time, a key capability ...
Analytical Chemistry
Apr 8, 2024
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42
Vanderbilt biochemists have discovered that the process bacteria undergo when they become drug resistant can act as a powerful tool for drug discovery.
Biochemistry
Jan 25, 2013
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0
A newly developed compound starves cancer cells by attacking their "power plants"—the so-called mitochondria. The new compound prevents the genetic information within mitochondria from being read. Researchers from the Max ...
Molecular & Computational biology
Dec 22, 2020
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16
Most malaria drugs are designed to reduce symptoms after infection. They work by blocking replication of the disease-causing parasites in human blood, but they don't prevent infection or transmission via mosquitoes. What's ...
Cell & Microbiology
Dec 6, 2018
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64
Anti-diabetic drugs may become cheaper and more accessible thanks to a breakthrough from CSIRO, Australia's national science agency.
Bio & Medicine
Oct 1, 2019
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17
The identification of compounds that could be promising candidates for drug development has become easier following research by the Walter and Eliza Hall Institute's medicinal chemistry group.
Biochemistry
Mar 24, 2010
0
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