Team discovers rules for breaking into Pseudomonas

Researchers report in the journal Nature that they have found a way to get antibacterial drugs through the nearly impenetrable outer membrane of Pseudomonas aeruginosa, a bacterium that—once it infects a person—is notoriously ...

New chemistry makes 'magic' drug improvements easier

In the last decade, scientists discovered a quirk of drug chemistry: If you add on a simple one-carbon building block to a drug, it can make the drug more potent, less toxic, or more stable.

Drugs from the deep: scientists explore ocean frontiers

Some send divers in speed boats, others dispatch submersible robots to search the seafloor, and one team deploys a "mud missile"—all tools used by scientists to scour the world's oceans for the next potent cancer treatment ...

Researchers cast neural nets to simulate molecular motion

New work from Los Alamos National Laboratory, the University of North Carolina at Chapel Hill, and the University of Florida is showing that artificial neural nets can be trained to encode quantum mechanical laws to describe ...

Supercomputing research opens doors for drug discovery

A quicker and cheaper technique to scan molecular databases developed at the Department of Energy's Oak Ridge National Laboratory could put scientists on the fast track to developing new drug treatments.

Unraveling plant reactions to injury

Better understanding of plant defense systems, and the potential to generate stress-tolerant plants and even new malaria drugs, may all stem from the documentation of a molecular mechanism that plays a significant role in ...

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