In the hunt for new medicines, any technique that expedites drug candidates into the clinic is a welcome advance. A team led by Hiroyuki Osada at the RIKEN Advanced Science Institute, Wako, recently developed a faster way ...
Analytical Chemistry
Sep 22, 2011
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In what could be a potential breakthrough in the battle against AIDS and a major development in the rational design of new drugs, scientists have engineered a new protein that prevents the virus from entering cells. This ...
Cell & Microbiology
Mar 31, 2011
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Retinitis pigmentosa (RP) is a cluster of genetically determined eye disorders that cause visual defects such as night blindness and narrowing of the field of vision, due to progressive loss of rod photoreceptors. As many ...
Cell & Microbiology
Mar 9, 2011
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If you can't stop the beta-amyloid protein plaques from forming in Alzheimer's disease patients, then maybe you can help the body rid itself of them instead. At least that's what scientists from New York were hoping for when ...
Cell & Microbiology
Mar 7, 2011
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A quicker and cheaper technique to scan molecular databases developed at the Department of Energy's Oak Ridge National Laboratory could put scientists on the fast track to developing new drug treatments.
Other
Dec 9, 2010
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Researchers have discovered a chemical that specifically blocks people's ability to detect the bitter aftertaste that comes with artificial sweeteners such as saccharin. The key is a molecule known only as GIV3727 that specifically ...
Biochemistry
May 27, 2010
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97
Using an unconventional approach that they designed, University of Pittsburgh drug discoverers and their collaborators at Walter Reed Army Institute of Research have identified compounds that hold promise for treating leishmaniasis, ...
Biochemistry
Nov 3, 2009
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Modern drug discovery is an expensive and complicated process. Hundreds of scientists and at least a decade are often required to produce a single medicine. One of the most critical steps in this process is the first one—identifying ...
Biochemistry
Apr 21, 2022
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10
Solutions to many real-world scientific and engineering problems—from improving weather models and designing new energy materials to understanding how the universe formed—require applications that can scale to a very ...
Software
Aug 1, 2018
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11
A new (and freely available) original research article by Barbara M. Zietek et al., now available ahead-of-print at SLAS Discovery Online, presents a fast, robust and accurate methodology for correlating compound identity ...
Biochemistry
Dec 21, 2017
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