For years, scientists have puzzled over what prompts the intertwined double-helix DNA to open its two strands and then start replication. Knowing this could be the key to understanding how organisms - from healthy cells to ...
Cell & Microbiology
Dec 13, 2016
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25
Analyzing DNA is useful for a number of vital applications. This includes diagnosis and monitoring of diseases, identification of criminals, and studying the function of a targeted segment of DNA. However, methods used for ...
Biochemistry
Mar 31, 2017
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8
Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered how a protein long known to be an essential activator of DNA replication actually triggers this process in cells.
Cell & Microbiology
Jan 7, 2010
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0
(Phys.org)—Genome editing for purposes of replication and repair is handled by enzymes called endonucleases, which cleave DNA strands at very specific sites. These are called "restriction sites," composed of palendromic ...
Enzo di Fabrizio and his team have developed a new technique to produce a direct image of the DNA helix and its inner structure. This is the first time scientists have ever been able to produce an image of DNA that allows ...
Biochemistry
Aug 31, 2015
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85
A research team from NPL and the University of Edinburgh have invented a new way to zip and unzip DNA strands using electrochemistry.
Biochemistry
Apr 18, 2013
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0
One of the most potent toxins known acts by welding the two strands of the famous double helix together in a unique fashion which foils the standard repair mechanisms cells use to protect their DNA.
Biochemistry
Aug 2, 2017
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138
An interdisciplinary team of researchers at the Hong Kong University of Science and Technology (HKUST) unraveled how a toxin released by Escherichia coli (E. coli) – a human gut bacteria, is connected to colorectal cancer, ...
Biochemistry
Sep 17, 2019
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89
For the first time, researchers at the University of California, Davis, have watched single strands of DNA being prepped for repair. The research, published this week in the journal Nature, has implications for understanding ...
Cell & Microbiology
Oct 29, 2012
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0
When large forces act on a heavy beam, for example, in bridge construction, the beam will be slightly deformed. Calculating the relationship between forces, internal stresses and deformations is one of the standard tasks ...
Molecular & Computational biology
Aug 5, 2020
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80
