DNA is a lengthy molecule—approximately 1,000-fold longer than the cell in which it resides—so it can't be jammed in haphazardly. Rather, it must be neatly organized so proteins involved in critical processes can access ...
If you've ever seen a picture of a DNA molecule, you probably saw it in its famous B-form: two strands coiling around each other in a right-handed fashion to form a double helix. But did you know that DNA can change its shape?
Researchers from the University of Illinois at Chicago are the first to describe why CRISPR gene editing sometimes fails to work, and how the process can be made to be much more efficient.
Cells propagate by making copies of themselves via genome replication. Arguably, replication of DNA is the most fundamental and conserved mechanism of all life forms. Cracking the secret of how this process is achieved with ...
The shape of DNA can be changed with a range of triggers including copper and oxygen—according to new research from the University of East Anglia.
It's been 65 years since the paper "Molecular structure of nucleic acids," by James Watson and Francis Crick, was published in Nature. Or, more prosaically, the paper that first describes the structure of DNA as we know it ...
It's DNA, but not as we know it. In a world first, Australian researchers have identified a new DNA structure—called the i-motif—inside cells. A twisted 'knot' of DNA, the i-motif has never before been directly seen inside ...
Not only can synthetic molecules mimic the structures of their biological models, they can also take on their functions and may even successfully compete with them, as an artificial DNA sequence designed by Ludwig-Maximilians-Universitaet ...
It may be the most famous structure in biology, but it wasn't until a few years ago that biophysicist Enzo di Fabrizio and his colleagues took the first direct images of the DNA double helix with an electron microscope.
If you had to copy billions of letters from one sheet of paper to another, you'd probably make a few mistakes. So it might not come as a surprise that when DNA makes a copy of its three-billion-base genetic code, it can slip ...
Sep 18, 2018
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