Catalyst adds fluorine-containing groups to make new compounds

Drugs that contain one or more fluorine atoms tend to be more stable, more powerful, and easier for the body to absorb. For those reasons, drug developers would like to be able to incorporate fluorine or a fluorine-containing ...

Protein engineers create new biocatalysts

Protein engineers at the California Institute of Technology (Caltech) have tapped into a hidden talent of one of nature's most versatile catalysts. The enzyme cytochrome P450 is nature's premier oxidation catalyst—a protein ...

Long-standing plant biochemistry mystery solved

Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and collaborators at the Karolinska Institute in Sweden have discovered how an enzyme "knows" where to insert a double bond when desaturating ...

Chemists devise better way to prepare workhorse molecules

In chemistry, so-called aromatic molecules compose a large and versatile family of chemical compounds that are the stuff of pharmaceuticals, electronic materials and consumer products ranging from sunscreen to plastic soda ...

Biosynthesis pathway of a new DNA nucleobase elucidated

DNA is composed of nucleobases represented by the letters A, T, G and C. They form the basis of the genetic code and are present in all living beings. But in a bacteriophage, another base, represented by the letter Z, exists. ...

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