A joint research team from KAIST and UCSD has developed a deep neural network named DeepTFactor that predicts transcription factors from protein sequences. DeepTFactor will serve as a useful tool for understanding the regulatory ...
Molecular & Computational biology
Jan 05, 2021
0
13
Exposure to mutagens, or mutation-causing agents, can not only bring about changes in DNA but also appear to induce errors when genes are transcribed to make proteins, which may be an important factor in age-related diseases.
Biotechnology
Dec 21, 2020
0
41
Although the DNA and its double-helix are one of the most familiar molecules of our time, our knowledge of how cells control what genes they want to express is still rather limited. In order to create, for example, an enzyme, ...
Molecular & Computational biology
Dec 03, 2020
1
91
A team of biomedical engineers at Duke University has created a new way to turn stem cells into a desired cell type by mastering the language of gene regulatory networks.
Biotechnology
Dec 01, 2020
0
29
Transcription factor proteins are the light switches of the human genome. By binding to DNA, they help turn genes 'on' or 'off' and start the important process of copying DNA into an RNA template that acts as a blueprint ...
Biotechnology
Oct 21, 2020
1
86
Life depends on an intricate game of hide-and-seek taking place inside the cell. New research, now published in the journal Nature, sheds light on the mechanisms with which DNA-binding proteins search the genome for their ...
Biotechnology
Jun 24, 2020
0
13
Transcription of genetic information is a fundamental process for life. If it does not work correctly, the consequences for the organism range from lethality to defects during development, genetic diseases, insufficient response ...
Molecular & Computational biology
Jun 04, 2020
0
5
While the first genome-wide DNA methylation map in mammalian cells was established over 10 years ago, such maps only provide snapshots and do not inform about the actual dynamics of this epigenetic mark. Researchers from ...
Biotechnology
Jun 02, 2020
0
16
A new compound has the potential to bind to DNA and activate genes, which could lead to new treatments for cancers and hereditary diseases. Zutao Yu, Ganesh Pandian Namasivayam, and Hiroshi Sugiyama of Kyoto University's ...
Biotechnology
Feb 28, 2020
0
16
Researchers from the group of Vlad Cojocaru together with colleagues the Max Planck Institute in Münster (Germany) have revealed how an essential protein helps to activate genomic DNA during the conversion of regular adult ...
Cell & Microbiology
Feb 14, 2020
0
21
